Medical supply firm Medline jumps more than 40% in debut after biggest IPO of 2025

Shares of U.S. medical supplies giant Medline jumped in its debut on the Nasdaq on Wednesday after the biggest initial public offering of the year globally.

The stock opened at $35, up from its $29 IPO price. Shares closed up more than 41% at $41 a share, bringing Medline’s market capitalization to roughly $54 billion.

The private equity-owned company sold a little over 216 million shares on Tuesday, raising $6.26 billion in an upsized offering that finished off a strong year for new listings and bolstered optimism about the IPO market in 2026. Shares of Medline will trade under the symbol MDLN.

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