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Medical supply firm Medline jumps more than 40% in debut after biggest IPO of 2025

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Shares of U.S. medical supplies giant Medline jumped in its debut on the Nasdaq on Wednesday after the biggest initial public offering of the year globally.

The stock opened at $35, up from its $29 IPO price. Shares closed up more than 41% at $41 a share, bringing Medline’s market capitalization to roughly $54 billion.

The private equity-owned company sold a little over 216 million shares on Tuesday, raising $6.26 billion in an upsized offering that finished off a strong year for new listings and bolstered optimism about the IPO market in 2026. Shares of Medline will trade under the symbol MDLN.

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